Gaelic cultural charity Cultarlann Inbhir Nis and The Gaelic Society of Inverness have secured funding to offer artists a £5,000 commission to create the new piece of art.
The piece could be a painting, tapestry or visual art.
It will be displayed at a new community-owned Gaelic cultural centre, which is being created in a former church in Inverness.
An inscribed flagstone dedicated to Màiri Mhòr was unveiled in Makars Court in Edinburgh two years ago, external.
Màiri Mhòr is buried in a graveyard near the new cultural centre.
Maggie Mullholland, of Cultarlann Inbhir Nis, said: “She was a passionate and defiant bard who condemned the Highland Clearances and was very much involved in the struggle for land reform, a cause still as relevant today as it was then.”
The Gaelic Society’s Murdo Campbell added: “Mairi Mhor, though originally from Skye, has strong connections with Inverness having married and brought up her family there .
“Her poems relate to the Clearances and persecution of crofters. It is fitting that she has something to remember her by in Inverness.”